A new study has found abnormal brain structures in the frontal lobe of cocaine users’ brains that are associated to their compulsive cocaine-using behaviour.
Researchers at the University of Cambridge led by Karen Ersche scanned the brains of 120 people, half of whom had a dependence on cocaine.
They found that the cocaine users had widespread loss of grey matter that was directly related to the duration of their cocaine abuse (i.e. the longer they had been using cocaine, the greater the loss of grey matter), and that this reduction in volume was associated with greater compulsivity to take cocaine.
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